Anti-KLC1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-KLC1 Polyclonal Antibody品牌:solarbio | 货号:K004056P

英文名称Anti-KLC1 Polyclonal Antibody
宿主Rabbit
别名KLC;KNS2;KNS2A
应用WB IHC IF
稀释比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量65kDa
Gene ID3831
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human KLC1
性状液体
Public Immunogen RangeRecombinant protein of human KLC1
Subcellular LocationsCell projection Cytoplasm Cytoplasmic vesicle cytoskeleton growth cone
Swiss ProtQ07866
克隆类型 Polyclonal Antibody
背景资料Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named “kinesin 2”, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

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