Anti-PSTPIP1PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
平台授权一级代理，咨询微信：jinshanbio
Anti-PSTPIP1 Polyclonal Antibody品牌：solarbio | 货号：K005446P| 英文名称 | Anti-PSTPIP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD2BP1;CD2BP1L;CD2BP1S;H-PIP;PAPAS;PSTPIP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 48kDa |
| Gene ID | 9051 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PSTPIP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PSTPIP1 |
| Subcellular Locations | Cell projection Cleavage furrow Cytoplasm cytoskeleton lamellipodium perinuclear region uropodium |
| Swiss Prot | O43586 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response. |
授权一级代理请认准金山科研平台，产品价格和货期请咨询微信：jinshanbio ，询价请加微信：jinshanbio
© 金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://brandmillipore.cn/thread-61206.htm
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://brandmillipore.cn/thread-61206.htm
特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系客服删除，本平台不提供信息校正和存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.
产品询价需求提交
猜你喜欢：
扫码添加客服微信，咨询产品报价
QQ:1749072012
热门标签
相关推荐
最近更新：
为你推荐：