Anti-DNAJC2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-DNAJC2 Polyclonal Antibody品牌:solarbio | 货号:K003832P

英文名称Anti-DNAJC2 Polyclonal Antibody
宿主Rabbit
别名MPHOSPH11;MPP11;ZRF1;ZUO1
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量72kDa
Gene ID27000
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human DNAJC2
性状液体
Public Immunogen RangeRecombinant protein of human DNAJC2
Subcellular LocationsCytoplasm Nucleus cytosol
Swiss ProtQ99543
克隆类型 Polyclonal Antibody
背景资料This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

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