Anti-ITGAVPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ITGAV Polyclonal Antibody品牌:solarbio | 货号:K007996P

英文名称Anti-ITGAV Polyclonal Antibody
宿主Rabbit
别名CD51;MSK8;VNRA;VTNR
应用IHC
稀释比例IHC 1:50-100.
交叉反应 Human Mouse
蛋白分子量116/112kDa
Gene ID3685
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ITGAV
性状液体
Public Immunogen RangeA synthetic peptide of human ITGAV
Subcellular LocationsCytoplasm Membrane
Swiss ProtP06756
克隆类型 Polyclonal Antibody
背景资料The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

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