Anti-SAV1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-SAV1 Polyclonal Antibody品牌:solarbio | 货号:K006142P

英文名称Anti-SAV1 Polyclonal Antibody
宿主Rabbit
别名SAV;WW45;WWP4
应用WB
稀释比例WB 1:1000-4000.
交叉反应 Human
蛋白分子量45kDa
Gene ID60485
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human SAV1
性状液体
Public Immunogen RangeRecombinant protein of human SAV1
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ9H4B6
克隆类型 Polyclonal Antibody
背景资料WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

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