Anti-RHOBPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-RHOB Polyclonal Antibody品牌:solarbio | 货号:K007376P

英文名称Anti-RHOB Polyclonal Antibody
宿主Rabbit
别名ARH6;ARHB;RHOH6
应用WB
稀释比例WB 1:1000-2000.
交叉反应 Human Mouse Rat
蛋白分子量22kDa
Gene ID388
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human RHOB
性状液体
Public Immunogen RangeA synthetic peptide of human RHOB
Subcellular LocationsCell membrane Endosome Membrane Nucleus
Swiss ProtP62745
克隆类型 Polyclonal Antibody
背景资料Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

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