Anti-MT-ND1PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-MT-ND1 Polyclonal Antibody品牌：solarbio | 货号：K007773P| 英文名称 | Anti-MT-ND1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MTND1;ND1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 36kDa |
| Gene ID | 4535 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MT-ND1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MT-ND1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P03886 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease. |
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