Anti-SPAG6PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-SPAG6 Polyclonal Antibody品牌:solarbio | 货号:K007601P

英文名称Anti-SPAG6 Polyclonal Antibody
宿主Rabbit
别名pf16;Repro-SA-1
应用WB
稀释比例WB 1:200-1000.
交叉反应 Human Mouse
蛋白分子量55kDa
Gene ID9576
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human SPAG6
性状液体
Public Immunogen RangeA synthetic peptide of human SPAG6
Swiss ProtO75602
克隆类型 Polyclonal Antibody
背景资料The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm.

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