Anti-RANKPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-RANK Polyclonal Antibody品牌:solarbio | 货号:K106460P

英文名称Anti-RANK Polyclonal Antibody
宿主Rabbit
别名ODFR;CD265;FEO;LOH18CR1;TNFRSF11A
应用WB
稀释比例WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量56kDa
Gene ID8792
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human RANK
性状液体
Public Immunogen RangeA synthetic peptide of human RANK
Subcellular LocationsCell membrane
Swiss ProtQ9Y6Q6
克隆类型 Polyclonal Antibody
背景资料CD265 is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine CD265 share 81% amino acid identity in their extracellular domains. CD265 is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. CD265 is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265.

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