Anti-COPS5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-COPS5 Polyclonal Antibody品牌:solarbio | 货号:K006779P

英文名称Anti-COPS5 Polyclonal Antibody
宿主Rabbit
别名CSN5;JAB1;SGN5;MOV-34
应用WB IHC
稀释比例WB 1:1000-5000. IHC 1:150-500.
交叉反应 Human Mouse
蛋白分子量38kDa
Gene ID10987
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human COPS5
性状液体
Public Immunogen RangeRecombinant protein of human COPS5
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ92905
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors

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