Anti-ANGPTL4PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ANGPTL4 Polyclonal Antibody品牌:solarbio | 货号:K006664P

英文名称Anti-ANGPTL4 Polyclonal Antibody
宿主Rabbit
别名NL2;ARP4;FIAF;PGAR;HFARP;pp1158;ANGPTL2
应用IHC
稀释比例IHC 1:25-100.
交叉反应 Human
蛋白分子量45kDa
Gene ID51129
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ANGPTL4
性状液体
Public Immunogen RangeRecombinant protein of human ANGPTL4
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ9BY76
克隆类型 Polyclonal Antibody
背景资料This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

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