Anti-FLT3PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-FLT3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-FLT3 Polyclonal Antibody品牌：solarbio | 货号：K006909P

英文名称	Anti-FLT3 Polyclonal Antibody
宿主	Rabbit
别名	FLK2;STK1;CD135;FLK-2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse
蛋白分子量	113kDa
Gene ID	2322
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human FLT3
性状	液体
Public Immunogen Range	Recombinant protein of human FLT3
Subcellular Locations	Cell membrane
Swiss Prot	P36888
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

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