Anti-EID3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-EID3 Polyclonal Antibody品牌:solarbio | 货号:K007705P

英文名称Anti-EID3 Polyclonal Antibody
宿主Rabbit
别名NS4EB;NSE4B;NSMCE4B
应用WB IHC
稀释比例WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量38kDa
Gene ID493861
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human EID3
性状液体
Public Immunogen RangeA synthetic peptide of human EID3
Subcellular LocationsCytoplasm
Swiss ProtQ8N140
克隆类型 Polyclonal Antibody
背景资料EID3is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

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