Anti-ADRA2APolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ADRA2A Polyclonal Antibody品牌:solarbio | 货号:K008009P

英文名称Anti-ADRA2A Polyclonal Antibody
宿主Rabbit
别名ADRA2;ADRAR;ZNF32;ADRA2R;ALPHA2AAR
应用WB IHC
稀释比例WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量49kDa
Gene ID150
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ADRA2A
性状液体
Public Immunogen RangeA synthetic peptide of human ADRA2A
Subcellular LocationsMembrane
Swiss ProtP08913
克隆类型 Polyclonal Antibody
背景资料Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

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