Anti-MSH4PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-MSH4 Polyclonal Antibody品牌:solarbio | 货号:K008191P

英文名称Anti-MSH4 Polyclonal Antibody
宿主Rabbit
别名hMSH4;MutS protein homolog 4
应用IHC
稀释比例IHC 1:100-300.
交叉反应 Human Mouse
蛋白分子量105kDa
Gene ID4438
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human MSH4
性状液体
Public Immunogen RangeRecombinant protein of human MSH4
Subcellular LocationsCytoplasm Nucleus
Swiss ProtO15457
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

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