Anti-ITA2BPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ITA2B Polyclonal Antibody品牌:solarbio | 货号:K106413P

英文名称Anti-ITA2B Polyclonal Antibody
宿主Rabbit
别名ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
应用WB
稀释比例WB 1:3000.
交叉反应 Human
蛋白分子量113kDa
Gene ID3174
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ITA2B
性状液体
Public Immunogen RangeA synthetic peptide of human ITA2B
Subcellular LocationsCytoplasm Cell membrane
Swiss ProtP08514
克隆类型 Polyclonal Antibody
背景资料Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

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