Anti-IL-6RalphaPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-IL-6R alpha Polyclonal Antibody品牌:solarbio | 货号:K106877P

英文名称Anti-IL-6R alpha Polyclonal Antibody
宿主Rabbit
别名IL6R;CD126;IL-6R-1;IL-6RA;IL6Q;IL6RA;IL6RQ;gp80;interleukin 6 receptor
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human
蛋白分子量52kDa
Gene ID16194
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human IL-6R alpha
性状液体
Public Immunogen RangeA synthetic peptide of human IL-6R alpha
Subcellular LocationsCell membrane Secreted
Swiss ProtP08887
克隆类型 Polyclonal Antibody
背景资料This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

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