Anti-CNTFRPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CNTFR Polyclonal Antibody品牌:solarbio | 货号:K003463P

英文名称Anti-CNTFR Polyclonal Antibody
宿主Rabbit
别名CNTFR
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量41kDa
Gene ID1271
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CNTFR
性状液体
Public Immunogen RangeRecombinant protein of human CNTFR
Subcellular LocationsCell membrane GPI-anchor Lipid-anchor
Swiss ProtP26992
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

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