Anti-TSG101PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-TSG101 Polyclonal Antibody品牌:solarbio | 货号:K006850P

英文名称Anti-TSG101 Polyclonal Antibody
宿主Rabbit
别名TSG10;VPS23
应用IHC
稀释比例IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量44kDa
Gene ID7251
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human TSG101
性状液体
Public Immunogen RangeRecombinant protein of human TSG101
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ99816
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

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