Anti-C8orf4PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-C8orf4 Polyclonal Antibody品牌:solarbio | 货号:K004382P

英文名称Anti-C8orf4 Polyclonal Antibody
宿主Rabbit
别名TC-1;TC1
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量12kDa
Gene ID56892
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human C8orf4
性状液体
Public Immunogen RangeRecombinant protein of human C8orf4
Subcellular LocationsCytoplasm Nucleus Nucleus speckle nucleolus
Swiss ProtQ9NR00
克隆类型 Polyclonal Antibody
背景资料This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

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