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Anti-PEX5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PEX5 Polyclonal Antibody品牌：solarbio | 货号：K004208P

英文名称	Anti-PEX5 Polyclonal Antibody
宿主	Rabbit
别名	PBD2A;PBD2B;PTS1-BP;PTS1R;PXR1;RCDP5
应用	WB IHC IF
稀释比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	71kDa
Gene ID	5830
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human PEX5
性状	液体
Public Immunogen Range	Recombinant protein of human PEX5
Subcellular Locations	Cytoplasm Peripheral membrane protein Peroxisome membrane
Swiss Prot	P50542
克隆类型	Polyclonal Antibody
背景资料	The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

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