Anti-ACVR1PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-ACVR1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ACVR1 Polyclonal Antibody品牌：solarbio | 货号：K008353P

英文名称	Anti-ACVR1 Polyclonal Antibody
宿主	Rabbit
别名	FOP;ALK2;SKR1;TSRI;ACTRI;ACVR1A;ACVRLK2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	57kDa
Gene ID	90
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human ACVR1
性状	液体
Public Immunogen Range	Recombinant protein of human ACVR1
Subcellular Locations	Cytoplasm
Swiss Prot	Q04771
克隆类型	Polyclonal Antibody
背景资料	Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

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