Anti-CNTNAP1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CNTNAP1 Polyclonal Antibody品牌:solarbio | 货号:K007992P

英文名称Anti-CNTNAP1 Polyclonal Antibody
宿主Rabbit
别名P190;CASPR;NRXN4;CNTNAP
应用WB IHC
稀释比例WB 1:200-1000. IHC 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量156kDa
Gene ID8506
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human CNTNAP1
性状液体
Public Immunogen RangeA synthetic peptide of human CNTNAP1
Subcellular LocationsCytoplasm
Swiss ProtP78357
克隆类型 Polyclonal Antibody
背景资料The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for ‘contactin-associated protein,’ includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

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