Anti-TRPM5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-TRPM5 Polyclonal Antibody品牌:solarbio | 货号:K007636P

英文名称Anti-TRPM5 Polyclonal Antibody
宿主Rabbit
别名MTR1;LTRPC5
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量131kDa
Gene ID29850
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human TRPM5
性状液体
Public Immunogen RangeA synthetic peptide of human TRPM5
Subcellular LocationsCytoplasm
Swiss ProtQ9NZQ8
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

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