Anti-HSPB8PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-HSPB8 Polyclonal Antibody品牌:solarbio | 货号:K006761P

英文名称Anti-HSPB8 Polyclonal Antibody
宿主Rabbit
别名H11;HMN2;CMT2L;DHMN2;E2IG1;HMN2A;HSP22
应用IHC
稀释比例IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量22kDa
Gene ID26353
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human HSPB8
性状液体
Public Immunogen RangeRecombinant protein of human HSPB8
Subcellular LocationsCytoplasm
Swiss ProtQ9UJY1
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

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