Anti-PIK3C2APolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-PIK3C2APolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-PIK3C2A Polyclonal Antibody品牌：solarbio | 货号：K005897P

英文名称	Anti-PIK3C2A Polyclonal Antibody
宿主	Rabbit
别名	CPK;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha
应用	WB IHC IP
稀释比例	WB 1:500-2000. IHC 1:50-100. IP 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	191kDa
Gene ID	5286
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human PIK3C2A
性状	液体
Public Immunogen Range	Recombinant protein of human PIK3C2A
Subcellular Locations	Cell membrane Cytoplasm Cytoplasmic vesicle Golgi apparatus Nucleus clathrin-coated vesicle
Swiss Prot	O00443
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

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