Anti-PIK3C2APolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-PIK3C2A Polyclonal Antibody品牌：solarbio | 货号：K005897P| 英文名称 | Anti-PIK3C2A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CPK;PI3-K-C2(ALPHA);PI3-K-C2A;PI3K-C2-alpha;PI3K-C2alpha |
| 应用 | WB IHC IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 191kDa |
| Gene ID | 5286 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PIK3C2A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PIK3C2A |
| Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic vesicle Golgi apparatus Nucleus clathrin-coated vesicle |
| Swiss Prot | O00443 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. |
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