Anti-RFX5PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-RFX5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-RFX5 Polyclonal Antibody品牌：solarbio | 货号：K004902P

英文名称	Anti-RFX5 Polyclonal Antibody
宿主	Rabbit
别名	RFX5
应用	WB IF
稀释比例	WB 1:500-2000. IF 1:50-100.
交叉反应	Human
蛋白分子量	65kDa
Gene ID	5993
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human RFX5
性状	液体
Public Immunogen Range	Recombinant protein of human RFX5
Subcellular Locations	Nucleus
Swiss Prot	P48382
克隆类型	Polyclonal Antibody
背景资料	A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.

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