Anti-FBLN5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-FBLN5 Polyclonal Antibody品牌:solarbio | 货号:K006131P

英文名称Anti-FBLN5 Polyclonal Antibody
宿主Rabbit
别名ADCL2;ARCL1A;ARMD3;DANCE;EVEC;FIBL-5;HNARMD;UP50
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量50kDa
Gene ID10516
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human FBLN5
性状液体
Public Immunogen RangeRecombinant protein of human FBLN5
Subcellular LocationsSecreted extracellular matrix extracellular space
Swiss ProtQ9UBX5
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

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