Anti-ANGPT1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ANGPT1 Polyclonal Antibody品牌:solarbio | 货号:K005523P

英文名称Anti-ANGPT1 Polyclonal Antibody
宿主Rabbit
别名AGP1;AGPT;ANG1
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse
蛋白分子量58kDa
Gene ID284
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ANGPT1
性状液体
Public Immunogen RangeRecombinant protein of human ANGPT1
Subcellular LocationsSecreted
Swiss ProtQ15389
克隆类型 Polyclonal Antibody
背景资料This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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