Anti-PORPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-POR Polyclonal Antibody品牌:solarbio | 货号:K005679P

英文名称Anti-POR Polyclonal Antibody
宿主Rabbit
别名CPR;CYPOR;P450R
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量77kDa
Gene ID5447
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human POR
性状液体
Public Immunogen RangeRecombinant protein of human POR
Subcellular LocationsEndoplasmic reticulum membrane Peripheral membrane protein
Swiss ProtP16435
克隆类型 Polyclonal Antibody
背景资料This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

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