Anti-DR1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-DR1 Polyclonal Antibody品牌:solarbio | 货号:K008024P

英文名称Anti-DR1 Polyclonal Antibody
宿主Rabbit
别名NC2;NC2B;NC2-BETA
应用IHC
稀释比例IHC 1:20-100.
交叉反应 Human Mouse Rat
蛋白分子量19kDa
Gene ID1810
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human DR1
性状液体
Public Immunogen RangeA synthetic peptide of human DR1
Subcellular LocationsNucleus
Swiss ProtQ01658
克隆类型 Polyclonal Antibody
背景资料This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

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