Anti-FBXW7PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

平台授权一级代理,咨询微信:jinshanbio

Anti-FBXW7 Polyclonal Antibody品牌:solarbio | 货号:K004271P

英文名称Anti-FBXW7 Polyclonal Antibody
宿主Rabbit
别名AGO;CDC4;FBW6;FBW7;FBX30;FBXO30;FBXW6;SEL-10;SEL10;hAgo;hCdc4
应用WB IHC IF
稀释比例WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量80kDa
Gene ID55294
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human FBXW7
性状液体
Public Immunogen RangeRecombinant protein of human FBXW7
Subcellular LocationsCytoplasm Nucleus nucleolus nucleoplasm
Swiss ProtQ969H0
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene’s potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene.

授权一级代理请认准金山科研平台,产品价格和货期请咨询微信:jinshanbio ,询价请加微信:jinshanbio

© 金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://brandmillipore.cn/thread-61369.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价