Anti-SF3B3PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-SF3B3 Polyclonal Antibody品牌:solarbio | 货号:K004347P

英文名称Anti-SF3B3 Polyclonal Antibody
宿主Rabbit
别名RSE1;SAP130;SF3b130;STAF130
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量136kDa
Gene ID23450
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human SF3B3
性状液体
Public Immunogen RangeRecombinant protein of human SF3B3
Subcellular LocationsNucleus
Swiss ProtQ15393
克隆类型 Polyclonal Antibody
背景资料This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron’s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

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