Anti-ALS2PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ALS2 Polyclonal Antibody品牌:solarbio | 货号:K005033P

英文名称Anti-ALS2 Polyclonal Antibody
宿主Rabbit
别名ALS2CR6;ALSJ;IAHSP;PLSJ
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量184kDa
Gene ID57679
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ALS2
性状液体
Public Immunogen RangeRecombinant protein of human ALS2
Subcellular LocationsCytoskeleton Cytosol Endosome
Swiss ProtQ96Q42
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

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