Anti-TAB1PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-TAB1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-TAB1 Polyclonal Antibody品牌：solarbio | 货号：K008371P

英文名称	Anti-TAB1 Polyclonal Antibody
宿主	Rabbit
别名	TAB 1;TAK1;TGF beta activated kinase 1 binding protein 1;MAP3K7IP 1
应用	WB IHC
稀释比例	WB 1:200-1000. IHC 1:100-300.
交叉反应	Human Mouse
蛋白分子量	55kDa
Gene ID	10454
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human TAB1
性状	液体
Public Immunogen Range	Recombinant protein of human TAB1
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q15750
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.

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