Anti-KRTAP11-1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-KRTAP11-1 Polyclonal Antibody品牌:solarbio | 货号:K007937P

英文名称Anti-KRTAP11-1 Polyclonal Antibody
宿主Rabbit
别名HACL1;HACL-1;KAP11.1
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量17kDa
Gene ID337880
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human KRTAP11-1
性状液体
Public Immunogen RangeA synthetic peptide of human KRTAP11-1
Swiss ProtQ8IUC1
克隆类型 Polyclonal Antibody
背景资料Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are -keratins and keratin-associated proteins (KRTAPs or KAPs), each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS), which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT), which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19.

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