Anti-CDK9PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CDK9 Polyclonal Antibody品牌:solarbio | 货号:K006698P

英文名称Anti-CDK9 Polyclonal Antibody
宿主Rabbit
别名TAK;C-2k;CTK1;CDC2L4;PITALRE
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量43kDa
Gene ID1025
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CDK9
性状液体
Public Immunogen RangeRecombinant protein of human CDK9
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP50750
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

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