Anti-CD33PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-CD33 Polyclonal Antibody品牌：solarbio | 货号：K006979P| 英文名称 | Anti-CD33 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | p67;SIGLEC3;SIGLEC-3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 40kDa |
| Gene ID | 945 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD33 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD33 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P20138 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CD33or Siglec-3 is atransmembrane receptorexpressed on cells ofmyeloidlineage.It is usually considered myeloid-specific, but it can also be found on somelymphoidcells. Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
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