Anti-CD33PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CD33 Polyclonal Antibody品牌:solarbio | 货号:K006979P

英文名称Anti-CD33 Polyclonal Antibody
宿主Rabbit
别名p67;SIGLEC3;SIGLEC-3
应用WB IHC
稀释比例WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量40kDa
Gene ID945
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CD33
性状液体
Public Immunogen RangeRecombinant protein of human CD33
Subcellular LocationsCytoplasm
Swiss ProtP20138
克隆类型 Polyclonal Antibody
背景资料CD33or Siglec-3 is atransmembrane receptorexpressed on cells ofmyeloidlineage.It is usually considered myeloid-specific, but it can also be found on somelymphoidcells. Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

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