Anti-CTSCPolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-CTSCPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CTSC Polyclonal Antibody品牌：solarbio | 货号：K005811P

英文名称	Anti-CTSC Polyclonal Antibody
宿主	Rabbit
别名	CPPI;DPP-I;DPP1;DPPI;HMS;JP;JPD;PALS;PDON1;PLS
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	52kDa
Gene ID	1075
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human CTSC
性状	液体
Public Immunogen Range	Recombinant protein of human CTSC
Subcellular Locations	Lysosome
Swiss Prot	P53634
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

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