Anti-SART1PolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-SART1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-SART1 Polyclonal Antibody品牌：solarbio | 货号：K005919P

英文名称	Anti-SART1 Polyclonal Antibody
宿主	Rabbit
别名	Ara1;HOMS1;SART1259;SNRNP110;Snu66
应用	WB IP
稀释比例	WB 1:500-2000. IP 1:20-50.
交叉反应	Human Mouse Rat
蛋白分子量	90kDa
Gene ID	9092
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human SART1
性状	液体
Public Immunogen Range	Recombinant protein of human SART1
Subcellular Locations	Nucleus
Swiss Prot	O43290
克隆类型	Polyclonal Antibody
背景资料	This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

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