Anti-ASGR1PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ASGR1 Polyclonal Antibody品牌:solarbio | 货号:K004830P

英文名称Anti-ASGR1 Polyclonal Antibody
宿主Rabbit
别名ASGPR;ASGPR1;CLEC4H1;HL-1
应用WB IHC
稀释比例WB 1:1000-4000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量33kDa
Gene ID432
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ASGR1
性状液体
Public Immunogen RangeRecombinant protein of human ASGR1
Subcellular LocationsMembrane Secreted Single-pass type II membrane protein
Swiss ProtP07306
克隆类型 Polyclonal Antibody
背景资料This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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