Anti-ANP32EPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ANP32E Polyclonal Antibody品牌:solarbio | 货号:K007756P

英文名称Anti-ANP32E Polyclonal Antibody
宿主Rabbit
别名LANPL;LANP-L
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量31kDa
Gene ID81611
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ANP32E
性状液体
Public Immunogen RangeA synthetic peptide of human ANP32E
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ9BTT0
克隆类型 Polyclonal Antibody
背景资料The Anp32 family consists of 32 evolutionarily-conserved proteins and is included within the superfamily of leucine-rich repeat (LRR) proteins. Leucine-rich acidic nuclear protein-like (LANPL), also called ANP32E or Cpd1, is a member of the Anp32 family. LANPL is located in the cytoplasm of peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It has also been detected in the nucleus, cytoplasm and membrane of multiple brain regions. Upon phosphorylation, LANPL colocalizes and inhibits protein phosphatase 2A (PP2A), but does not inhibit PP1. LANPL modulates cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development and cerebellar morphogenesis.

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