Anti-L1CAMPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-L1CAM Polyclonal Antibody品牌:solarbio | 货号:K005910P

英文名称Anti-L1CAM Polyclonal Antibody
宿主Rabbit
别名CAML1;CD171;HSAS;HSAS1;MASA;MIC5;N-CAM-L1;N-CAML1;NCAM-L1;S10;SPG1
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量140kDa
Gene ID3897
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human L1CAM
性状液体
Public Immunogen RangeRecombinant protein of human L1CAM
Subcellular LocationsCell membrane Cell projection Single-pass type I membrane protein growth cone
Swiss ProtP32004
克隆类型 Polyclonal Antibody
背景资料The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

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