Anti-PAK4PolyclonalAntibody-一抗-抗体-蛋白与免疫
2023-10-29
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Anti-PAK4 Polyclonal Antibody品牌：solarbio | 货号：K008214P| 英文名称 | Anti-PAK4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KIAA1142;Serine/threonine-protein kinase PAK 4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 64kDa |
| Gene ID | 10298 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PAK4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PAK4 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O96013 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
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