Anti-ANPEPPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-ANPEP Polyclonal Antibody品牌:solarbio | 货号:K007597P

英文名称Anti-ANPEP Polyclonal Antibody
宿主Rabbit
别名APN;CD13;LAP1;P150;PEPN;GP150
应用IHC
稀释比例IHC 1:100-300.
交叉反应 Human Mouse Rat
蛋白分子量110kDa
Gene ID290
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human ANPEP
性状液体
Public Immunogen RangeA synthetic peptide of human ANPEP
Subcellular LocationsCytoplasm
Swiss ProtP15144
克隆类型 Polyclonal Antibody
背景资料Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS.

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