Anti-CYP3A5PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CYP3A5 Polyclonal Antibody品牌:solarbio | 货号:K005379P

英文名称Anti-CYP3A5 Polyclonal Antibody
宿主Rabbit
别名CP35;CYPIIIA5;P450PCN3;PCN3
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量57kDa
Gene ID1577
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CYP3A5
性状液体
Public Immunogen RangeRecombinant protein of human CYP3A5
Subcellular LocationsEndoplasmic reticulum membrane Microsome membrane Peripheral membrane protein
Swiss ProtP20815
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

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