Anti-CCR8PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CCR8 Polyclonal Antibody品牌:solarbio | 货号:K005633P

英文名称Anti-CCR8 Polyclonal Antibody
宿主Rabbit
别名CC-CKR-8;CCR-8;CDw198;CKRL1;CMKBR8;CMKBRL2;CY6;GPRCY6;TER1
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量41kDa
Gene ID1237
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CCR8
性状液体
Public Immunogen RangeRecombinant protein of human CCR8
Subcellular LocationsCell membrane Multi-pass membrane protein
Swiss ProtP51685
克隆类型 Polyclonal Antibody
背景资料This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

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