Anti-CADPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-CAD Polyclonal Antibody品牌:solarbio | 货号:K005771P

英文名称Anti-CAD Polyclonal Antibody
宿主Rabbit
别名CDG1Z;EIEE50;GATD4
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:50-100.
交叉反应 Human
蛋白分子量243kDa
Gene ID790
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CAD
性状液体
Public Immunogen RangeRecombinant protein of human CAD
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP27708
克隆类型 Polyclonal Antibody
背景资料The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.

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