Anti-BCCIPPolyclonalAntibody-一抗-抗体-蛋白与免疫-耗材-金山科研平台 Bio-Rad伯乐官网 |伯乐授权代理 |伯乐ddPCR| 伯乐Aminex| 伯乐层析填料色谱柱

Anti-BCCIPPolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-BCCIP Polyclonal Antibody品牌：solarbio | 货号：K005929P

英文名称	Anti-BCCIP Polyclonal Antibody
宿主	Rabbit
别名	TOK-1;TOK1
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:100-200.
交叉反应	Human Mouse Rat
蛋白分子量	36kDa
Gene ID	56647
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human BCCIP
性状	液体
Public Immunogen Range	Recombinant protein of human BCCIP
Subcellular Locations	Nucleus
Swiss Prot	Q9P287
克隆类型	Polyclonal Antibody
背景资料	This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

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