Anti-RPL22PolyclonalAntibody-一抗-抗体-蛋白与免疫

2023-10-29

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Anti-RPL22 Polyclonal Antibody品牌:solarbio | 货号:K006013P

英文名称Anti-RPL22 Polyclonal Antibody
宿主Rabbit
别名EAP;HBP15;HBP15/L22;L22
应用WB
稀释比例WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量15kDa
Gene ID6146
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human RPL22
性状液体
Public Immunogen RangeRecombinant protein of human RPL22
Subcellular LocationsCytosol Nucleus secreted
Swiss ProtP35268
克隆类型 Polyclonal Antibody
背景资料Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

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